Sinovac showed efficacy of 50.4%

[Lala81]

13 minutes ago, Staff69 said:

just sharing 

 

 

 General efficacy is different from clinical efficacy. 50.4% includes preventing asymptomatic transmission.

General efficacy, which includes asymptomatic transmission and the transferring of clinical data onto the general public, is normally far lower than clinical efficacy. Including asymptomatic infections into the datas would definitely further lower the efficacy, be it clinical or general.

According to Butantã Institute (the lab that developed the vaccine in Brazil), it is proved to have 100% protection against severe symptoms of COVID-19 and 78% effectiveness against mild cases.

As a reference, the efficacy of Oxford/AZ vaccine against asymptomatic infections is 59% (study done by a third party) and hasn’t been transferred onto real-life scenario. Pfizer and Moderna didn’t release any datas regarding asymptomatic infections and general efficacy.

https://www.bmj.com/content/371/bmj.m4777

yes. It's not an apple to apple comparison. It would require the specialists to really dive down into data, or subgroup analysis of the trial data.

 

[Jamesc]

Why people say making vaccines is so difficult.

There are 65 vaccines being made and 20 are on final testing.

If it's so hard then one also cannot be made.

[Jusnel]

All vaccines are good vaccines. 

I dont know where I learn this from. 

[noobcarbuyer]

12 hours ago, Sosaria said:

Then got to wait 3-4 years till the pandemic dies out, like spanish flu took a couple of years as well.

https://www.nejm.org/doi/full/10.1056/nejmp0904819

The "Spanish Flu" never went away or died out.  As Anthony S. Fauci (co-author of the article above) explained, the descendants of the 1918 influenza virus have contributed to a “pandemic era” that has lasted the past hundred years. In fact, all the pandemics since (1957, 1968, 2009) are all derivatives of the 1918 flu . In 2009, the H1N1 influenza virus in public circulation was a fourth-generation descendant of the novel virus from 1918. The flu viruses that people get this year, or last year, are all still directly related to the 1918 ancestor.

https://www.nytimes.com/2021/01/12/health/coronavirus-immunity-future.html

Most likely, this pandemic will not 'die out' and instead the COVID-19 strain will become endemic like one of the common cold strains circulating, with yearly vaccinations required. 

[noobcarbuyer]

2 hours ago, Staff69 said:

just sharing . author rebecca lim

 

 

 General efficacy is different from clinical efficacy. 50.4% includes preventing asymptomatic transmission.

General efficacy, which includes asymptomatic transmission and the transferring of clinical data onto the general public, is normally far lower than clinical efficacy. Including asymptomatic infections into the datas would definitely further lower the efficacy, be it clinical or general.

According to Butantã Institute (the lab that developed the vaccine in Brazil), it is proved to have 100% protection against severe symptoms of COVID-19 and 78% effectiveness against mild cases.

As a reference, the efficacy of Oxford/AZ vaccine against asymptomatic infections is 59% (study done by a third party) and hasn’t been transferred onto real-life scenario. Pfizer and Moderna didn’t release any datas regarding asymptomatic infections and general efficacy.

https://www.bmj.com/content/371/bmj.m4777

My textbook memory must be rusty.

For vaccines, the terminology of "efficacy" is used exclusively to describe how well vaccines prevent infection and/or transmission during clinic trials (i.e optimal conditions, healthy volunteers with no pre-existing conditions, controlled environment). 

In real world usage, the correct terminology would be to use "effectiveness" to describe the vaccine's performance.

To be honest, the Sinovac's efficacy of 50% (data from the late stage brazil clinical trials) may translate to real world effectiveness of 30%-40%. Not great, not terrible. 

[Beregond]

3 hours ago, Jamesc said:

Why people say making vaccines is so difficult.

There are 65 vaccines being made and 20 are on final testing.

If it's so hard then one also cannot be made.

saw the test figure give by 3 country.  i would say its very buay zhun, properly less then 50% like u say .

2 country test on 1k over ppl, 1 country test on 10k ppl . the % vary from 70+ -50+ . no 1 know the real accurate figure expect china now.

if their vaccine dun upgrade or improve, in the end only 3rd world country will buy from them.

cheap and available and easy to transport. 

[Wt_know]

everything Made in China (MIC) .... FTW !!!

faster, better, cheaper ... that's our ambition too ... LOL

Edited January 14, 2021 by Wt_know

[Somewhat1975]

PPT from Brazil presentation for Sinovac vaccine

There was no record of any adverse events related to the vaccine. In terms of allergic reactions, the frequency of occurrence was low, 0.3%, similar among those who received vaccine and placebo.

1&2)  ICU and hospitalization ( 0 from the vaccinated group, 7 from the placebo group)

3) Light  symptom which needs medical assistance  (7 from the vaccinated group, (31-7=24) from the placebo group)

4) very light symptom and do not need medical assistance ((85-7=78) from the vaccinated group, (167--31=136) from the placebo group)

 

Unlike other diseases, the majority of the covid patient has a very mild symptom, which does not need hospitalization or medication. This makes it difficult to compare the results of different vaccine trials difficult. The confirmation of infection was done through the PCR test. PCR test was only carried out after the participants self-report their covid-related symptoms. In the presentation, the Brazilian claimed they captured more very light symptoms cases compared to other trials because 100% of their participants were frontline healthcare workers, who supposedly better at self-diagnosis of covid symptoms and more likely to report their symptoms. 

 

 

[Jamesc]

Quote

 

The covid-19 vaccine candidate developed by the University of Oxford is 90% effective when a person is initially given a half dose followed by a full dose, interim phase III trial results show.

 

Maybe just give our body a small taste of the enemy virus in the first dose and our body start ramping up our full defense.

Then we get the full dose of the enemy virus in the second vaccination our body is fully prepared to to wipe out the enemy after that.

[Jamesc]

No adverse events maybe means the vaccine don't hurt our body

but there again maybe it doesn't hurt the virus too!

Its like this idiot telling everyone drinking warm water will kill the virus.

Of course drinking warm water there was no adverse reaction by the body

but the warm water also didn't have an adverse reaction on the virus.

The virus will lose!!!!

 

[Jamesc]

I am not an expert on the virus

but I have a great nose for bull sheet

and I can recognise an idiot giving

stupid and more importantly

dangerous advice when I hear it!

 

 

[Jamesc]

Why need to waste so much time and money when warm water would have wiped out the virus?

Why no one listen to this genius?

Quote

KUALA LUMPUR - Malaysia's Health Minister Adham Baba has accused the previous Pakatan Harapan (PH) government of failing to contain the Tabligh Covid-19 cluster, which grew to become the country's biggest source of infections.

See lah they never tell everyone to drink warm water and now so many people have the infection.

Edited January 14, 2021 by Jamesc

[Vinyl]

1 hour ago, Beregond said:

saw the test figure give by 3 country.  i would say its very buay zhun, properly less then 50% like u say .

2 country test on 1k over ppl, 1 country test on 10k ppl . the % vary from 70+ -50+ . no 1 know the real accurate figure expect china now.

 if their vaccine dun upgrade or improve, in the end only 3rd world country will buy from them.

cheap and available and easy to transport. 

Sinovac has done themselves no favour by releasing the results in this manner. Too much details.

Pfizer-BioNtech didn't even give details and nobody question their > 90% figures.

What's actually important is that, Sinovac CoronaVac is 100% effective in preventing severe cases.

It's too late now actually, the bad press has dented public confidence in their vaccines.

 

Pfizer has their fair share of bad press but amdk, confidence in their vaccines are intact. 

https://www.nytimes.com/2020/12/16/health/covid-pfizer-vaccine-allergic-reaction.html

https://www.nytimes.com/2021/01/12/health/covid-vaccine-death.html

 

3rd world countries have no choice. Their people have to decide between dying of Covid or be injected with a vaccine with 50.4% efficacy.

[GoodCar]

The Title of this Topic is racist and not sensitive. I urge Admin or Moderator to change the title.

One can call title it as Sinovac or whatever, why use the word " Chinese"....and in the same context.....any race or ethnic group should not be used.

It falls into the group of "Chinese bashing" propaganda that is going around in the world by......your guess is better than mine

 

Once again, I urge Admin or Moderator to change the name of the title for a meaningful forum sharing of view here.

 

I miss those early day when there are less internet user and people  are generally more responsible and sensible in their post in the virtual world 

 

 

[bsswan]

6 minutes ago, GoodCar said:

The Title of this Topic is racist and not sensitive. I urge Admin or Moderator to change the title.

One can call title it as Sinovac or whatever, why use the word " Chinese"....and in the same context.....any race or ethnic group should not be used.

It falls into the group of "Chinese bashing" propaganda that is going around in the world by......your guess is better than mine

 

Once again, I urge Admin or Moderator to change the name of the title for a meaningful forum sharing of view here.

 

I miss those early day when there are less internet user and people  are generally more responsible and sensible in their post in the virtual world 

 

 

Not disagreeing with you but........ you know what "Sino" and "vac" means in Sinovac, right?

In it's simplest form, the title of the thread is a mere expansion of the actual vaccine name.

[GoodCar]

4 minutes ago, bsswan said:

Not disagreeing with you but........ you know what "Sino" and "vac" means in Sinovac, right?

In it's simplest form, the title of the thread is a mere expansion of the actual vaccine name.

Irregardless, this title is racist in nature.

Left uncheck, these poison will slowly flow into people's sub conscious mind. A techniq often deployed by the dark side for century.

Less people forget about our painful history and what is happening in the West and the State now.

Edited January 14, 2021 by GoodCar

[Beregond]

1 hour ago, Vinyl said:

 

3rd world countries have no choice. Their people have to decide between dying of Covid or be injected with a vaccine with 50.4% efficacy.

this is quite true.

those countries cannot lock down like us, they dun even test their ppl. 

the jumping of queue by various nations as mention by WHO make thing worst.

if got money got choice, of course every 1 would take pfizer like sg. 

but the fact is sometime even though the food on the table look like a joke to us. these 'joke' can save millions in 3rd world country 

[Atonchia]

Indonesia bought a lot right? 

Widodo got the 1st jab? 

Still get 50 percent chance 😅